TECH Brief 2 – Statistical Test for Accuracy Evaluation Single and Replicates

Accurate and reliable analytical results are paramount in science and industry where Certified Reference Materials (CRMs) are used to verify accuracy. In this Technical Brief, we use a statistical t-test modified to incorporate the stated measurement uncertainty of the CRM on a replicate analysis obtained from the analysis of a CRM. By integrating measurement uncertainty into the t-test framework, the test provides a more realistic representation of the accuracy of the obtained results. In addition, the accuracy of a single value obtained from an analysis of a CRM is demonstrated.